7. Acetaminophen (Tylenol) and alcohol
Tylenol and alcohol use the same enzyme to break down. For this reason it is recommended to wait around 6 hours between taking medicine containing acetaminophen and drinking alcohol. This pertains also to prescription and over-the-counter pain and cold medicines.
8. SSRIS and Opioids
Painkillers and antidepressants do not mix well. Some antidepressants increase the levels of serotonin, while some painkillers can have the same effect. Increased levels of serotonin may lead to high body temperature, agitation, and rapid breathing and heart rates.